What is the normal NIBUT in healthy dogs compared with dogs with EDED?

What is the normal NIBUT in healthy dogs compared with dogs with EDED?

• A. 20s vs <5s
• B. 21s vs <5s
• C. 24.2s vs 14.9s
• D. 20s vs 7s

Answer: (A)

Non-invasive tear film break-up time (NIBUT) measures how long the tear film remains uniform on the eye without using dye. In healthy dogs, the tear film stays stable for about 20 seconds on average. In dogs with evaporative dry eye disease (EDED), rapid tear film breakup occurs because the tear film is unstable, especially due to lipid layer issues that increase evaporation, so the NIBUT drops to under 5 seconds. This is why the best matched statement is that healthy dogs have around 20 seconds, while dogs with EDED have a NIBUT of less than 5 seconds.

Non-invasive tear film break-up time (NIBUT) measures how long the tear film remains uniform on the eye without using dye. In healthy dogs, the tear film stays stable for about 20 seconds on average. In dogs with evaporative dry eye disease (EDED), rapid tear film breakup occurs because the tear film is unstable, especially due to lipid layer issues that increase evaporation, so the NIBUT drops to under 5 seconds. This is why the best matched statement is that healthy dogs have around 20 seconds, while dogs with EDED have a NIBUT of less than 5 seconds.